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Here’s What We Know About ‘Stealth’ Omicron BA.2 — The More Infectious Subvariant Better Able To Infect Vaccinated People

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A detailed relative of the omicron coronavirus variant—often known as BA.2 and dubbed “stealth omicron” by some scientists—is extra infectious and higher at infecting vaccinated folks, a Danish study has discovered, sparking issues of an much more transmissible pressure because it quickly outpaces different variants world wide.

Key Details

Individuals contaminated with the BA.2 omicron subvariant had been round 33% extra prone to infect others than these contaminated with BA.1, the dominant and “unique” omicron kind, in accordance with an analysis of infections in additional than 8,500 Danish households by researchers at Denmark’s Statens Serum Institut (SSI), the College of Copenhagen, Statistics Denmark and the Technical College of Denmark.

The research, which has not but been peer reviewed, discovered that these uncovered to BA.2 of their family had a 39% probability of getting contaminated inside every week, whereas the chance for these uncovered to BA.1 was 29%.   

The BA.2 subvariant was higher at infecting vaccinated and booster-vaccinated folks than BA.1, the researchers discovered, although unvaccinated folks had been nonetheless extra prone to get contaminated and transmit the virus.    

Omicron BA.2 is “considerably extra transmissible than BA.1,” the researchers concluded, including that the sub-variant has properties that may scale back the safety in opposition to an infection provided by vaccines.

Early analyses from SSI present no variations in hospitalizations in comparison with BA.1.

The research is consistent with early data from the U.Okay Well being Safety Company (UKHSA), which discovered BA.2 to have an “elevated progress charge” in comparison with BA.1. 

Key Background 

Whereas three primary sub-lineages of omicron have been described world wide—BA.1, BA.2, and BA.3—BA.1 accounts for nearly all circumstances of omicron. BA.2 is, nonetheless, gaining floor in some international locations and outcompeting the “unique” omicron pressure. In Denmark, it shortly overtook BA.1 to change into the dominant kind, accounting for round a fifth of circumstances in late 2021, just below half within the second week of January and approximately 82% of circumstances as of early February. It’s also spreading in international locations together with Britain, France, India and Norway. Regardless of low case numbers, the UKHSA designated BA.2 a variant below investigation.

What To Watch For

A brand new variant. Whereas at the moment grouped below omicron, the genetic distinction between BA.1 and BA.2 “is larger than the distinction between the unique variant and the alpha variant,” the SSI stated. Such variations may result in a distinction in habits like severity or infectiousness, the SSI famous, however stated extra work wanted to be finished to search out out. “It’s anticipated that vaccines additionally have an impact in opposition to extreme sickness upon BA.2 an infection,” it added. 

What We Don’t Know

So much. Except for restricted proof on BA.2’s progress in some areas, there may be not quite a lot of knowledge on its habits, together with whether or not it’s higher capable of evade immunity, causes extra extreme sickness or how far more transmissible it could be over BA.1. Its genetic make-up could make it tougher to identify in some elements of the world, prompting some scientists to provide it the nickname “stealth omicron.” 

Additional Studying

Scientists find ‘stealth’ version of Omicron that may be harder to track (Guardian)

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